Synthesis of Five- and Six-MemberedN-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists
نویسندگان
چکیده
منابع مشابه
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.
N-Formyl peptide receptors (FPRs: FPR1, FPR2, and FPR3) are G protein-coupled receptors that play key roles in modulating immune cells. FPRs represent potentially important therapeutic targets for the development of drugs that could enhance endogenous anti-inflammation systems associated with various pathologies, thereby reducing the progression of inflammatory conditions. Previously, we identi...
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ژورنال
عنوان ژورنال: Drug Development Research
سال: 2016
ISSN: 0272-4391
DOI: 10.1002/ddr.21370